Publications
2021
Kim DH, Bang E, Ha S, Jung HJ, Choi YJ, Yu BP, Chung HY. Organ-differential Roles of Akt/FoxOs Axis as a Key Metabolic Modulator during Aging. Aging Dis. 2021 Oct 1;12(7):1713-1728.
Kim BM, Kim DH, Park YJ, Ha S, Choi YJ, Yu HS, Chung KW, Chung HY. PAR2 promotes high-fat diet-induced hepatic steatosis by inhibiting AMPK-mediated autophagy. J Nutr Biochem. 2021 Sep;95:108769.
2020
Kim DH, Bang E, Arulkumar R, Ha S, Chung KW, Park MH, Choi YJ, Yu BP, Chung HY. Senoinflammation: A major mediator underlying age-related metabolic dysregulation. Exp Gerontol. 2020 Feb 27:110891. doi: 10.1016/j.exger.2020.110891. [Epub ahead of print] Review
Liu Y, Chen X, Choi YJ, Yang N, Song Z, Snedecor ER, Liang W, Leung EL, Zhang L, Qin C, Chen J. GORAB promotes embryonic lung maturation through antagonizing AKT phosphorylation, versican expression, and mesenchymal cell migration. FASEB J. 2020 Feb 18. doi: 10.1096/fj.201902075R. [Epub ahead of print]
Kim DH, Bang E, Jung HJ, Noh SG, Yu BP, Choi YJ, Chung HY. Anti-aging Effects of Calorie Restriction (CR) and CR Mimetics based on the Senoinflammation Concept. Nutrients. 2020 Feb 6;12(2). pii: E422. doi: 10.3390/nu12020422. Review.
Lee AK, Kim DH, Bang E, Choi YJ, Chung HY. β-Hydroxybutyrate Suppresses Lipid Accumulation in Aged Liver through GPR109A-mediated Signaling. Aging Dis. 11(4):777-790, 2020
Kim DH, Kim BM, Chung KW, Choi YJ, Yu BP, Chung HY. Interaction between CHOP and FoxO6 promotes hepatic lipid accumulation. Liver Int. 40(11):2706-2718, 2020
Choi YJ. Shedding Light on the Effects of Calorie Restriction and its Mimetics on Skin Biology. Nutrients. 12(5):1529, 2020.
Kim DH, Bang E, Arulkumar R, Ha S, Chung KW, Park MH, Choi YJ, Yu BP, Chung HY. Senoinflammation: A major mediator underlying age-related metabolic dysregulation. Exp Gerontol. 134:110891, 2020
Liu Y, Chen X, Choi YJ, Yang N, Song Z, Snedecor ER, Liang W, Leung EL, Zhang L, Qin C, Chen J. GORAB promotes embryonic lung maturation through antagonizing AKT phosphorylation, versican expression, and mesenchymal cell migration. FASEB J. 34(4):4918-4933, 2020
Kim DH, Bang E, Jung HJ, Noh SG, Yu BP, Choi YJ, Chung HY. Anti-aging Effects of Calorie Restriction (CR) and CR Mimetics based on the Senoinflammation Concept. Nutrients. 6;12(2):422, 2020
Kim DH, Ha S, Choi YJ, Dong HH, Yu BP, Chung HY1. Altered FoxO1 and PPARγ interaction in age-related ER stress-induced hepatic steatosis. Aging (Albany NY). 2019 Jun 25;11(12):4125-4144.
2019
Kim DH, Ha S, Choi YJ, Dong HH, Yu BP, Chung HY. Altered FoxO1 and PPARγ interaction in age-related ER stress-induced hepatic steatosis. Aging (Albany NY). 2019 Jun 25;11(12):4125-4144.
Chung HY, Kim DH, Lee EK, Chung KW, Chung S, Lee B, Seo AY, Chung JH, Jung YS, Im E, Lee J, Kim ND, Choi YJ, Im DS, Yu BP. Redefining Chronic Inflammation in Aging and Age-Related Diseases: Proposal of the Senoinflammation Concept. Aging Dis. 2019 Apr 1;10(2):367-382.
Choi YJ, Laclef C, Yang N, Andreu-Cervera A, Lewis J, Mao X, Li L, Snedecor ER, Takemaru KI, Qin C, Schneider-Maunoury S, Shroyer KR, Hannun YA, Koch PJ, Clark RA, Payne AS, Kowalczyk AP, Chen J. RPGRIP1L is required for stabilizing epidermal keratinocyte adhesion through regulating desmoglein endocytosis. PLoS Genet. 2019 Jan 28;15(1):e1007914.
2017
Liu M, Clarke CJ, Salama MF, Choi YJ, Obeid LM, Hannun YA. Co-ordinated activation of classical and novel PKC isoforms is required for PMA-induced mTORC1 activation. PLoS One. 2017 Sep 19;12(9):e0184818.
Chung KW, Kim KM, Choi YJ, An HJ, Lee B, Kim DH, Lee EK, Im E, Lee J, Im DS, Yu BP, Chung HY. The critical role played by endotoxin-induced liver autophagy in the maintenance of lipid metabolism during sepsis. Autophagy. 2017 Jul 3;13(7):1113-1129.
Chung KW, Jeong HO, Lee B, Park D, Kim DH, Choi YJ, Lee EK, Kim KM, Park JW, Yu BP, Chung HY. Involvement of NF-κBIZ and related cytokines in age-associated renal fibrosis. Oncotarget. 2017 Jan 31;8(5):7315-7327.
2016
Kim CH, Lee EK, Choi YJ, An HJ, Jeong HO, Park D, Kim BC, Yu BP, Bhak J, Chung HY. Short-term calorie restriction ameliorates genomewide, age-related alterations in DNA methylation. Aging Cell. 2016 Dec:15(6):1074-1081.
Choi YJ, Moon KM, Chung KW, Jeong JW, Park D, Kim DH, Yu BP, Chung HY. The underlying mechanism of proinflammatory NF-κB activation by the mTORC2/Akt/IKKα pathway during skin aging. Oncotarget. 2016 Aug 16:7(33):52685-52694.
Toriyama M, Lee C, Taylor SP, Duran I, Cohn DH, Bruel AL, Tabler JM, Drew K, Kelly MR, Kim S, Park TJ, Braun D, Pierquin G, Biver A, Wagner K, Malfroot A, Panigrahi I, Franco B, Al-Lami HA, Yeung Y, Choi YJ; University of Washington Center for Mendelian Genomics, Duffourd Y, Faivre L, Rivière JB, Chen J, Liu KJ, Marcotte EM, Hildebrandt F, Thauvin-Robinet C, Krakow D, Jackson PK, Wallingford JB. The ciliopathy-associated CPLANE proteins direct basal body recruitment of intraflagellar transport machinery. Nat Genet. 2016 Jun;48(6):648-56.
Liu Y, Snedecor ER, Choi YJ, Yang N, Zhang X, Xu Y, Han Y, Jones EC, Shroyer KR, Clark RA, Zhang L, Qin C, Chen J. Gorab is required for dermal condensate cells to respond to hedgehog signals during hair follicle morphogenesis. J Invest Dermatol, 2016 Feb:136(2):378-386.